Kanye West pleads not guilty in battery case

FILE - This Sept. 7, 2012 file photo shows Kanye West at the Alexander Wang collection during Mercedes-Benz Fashion Week in New York. West pleaded not guilty through his attorney to misdemeanor battery and attempted grand theft charges in a Los Angeles court on Thursday Nov. 7, 2013. (Photo by Dario Cantatore/Invision/AP, File)

LOS ANGELES (AP) — Kanye West has pleaded not guilty to misdemeanor battery and attempted grand theft in a case filed over a scuffle with a celebrity photographer earlier this year.

Attorney Blair Berk entered the plea on the rapper's behalf Thursday in a Los Angeles court. West was charged with two misdemeanors in September over a July altercation with paparazzo Daniel Ramos at Los Angeles International Airport.

Prosecutors declined to file felony charges against West, but decided to pursue the misdemeanors. Each carries a penalty of up to six months in jail or a $1,000 fine.

Ramos claims West punched him in an unprovoked attack and wrestled his camera to the ground on July 19.

West's case is due back in court on Jan. 23.

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Source: http://news.yahoo.com/kanye-west-pleads-not-guilty-battery-case-181751592.html
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The Galaxy Note 3 Experience app shows you what using a Note is all about

Get a deeper look into the many features of Samsung's latest Note

Ever been curious about using a Note device, but never given one a try? Well Samsung is hoping that an app in the Play Store called the Galaxy Note 3 Experience will help you discover all of its great features. You get a chance to watch some promo videos, and live interactive full-screen tutorials showing how features work on the Note 3 on whatever device you currently use.

Things like Air Command, Multi Window, Scrapbook and more are all on display, and they actually look pretty good considering that everything is just running in an app. You can also see how interactions work between the Galaxy Note 3 and the Galaxy Gear, although that implementation is a little clunky to our eyes.

The app also does you some good even if you already have made the choice to go with a Note 3. If you install it on your device, you'll get tutorials on all of the great features at your disposal that you may not have discovered on your own. If you're at all curious about the Note 3, you may want to take a look.

Source: http://feedproxy.google.com/~r/androidcentral/~3/kO_PA_0hhoY/story01.htm
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French Ruling Puts Google Between a Rock and an Orgy

Max Mosley may have used poor judgment when he trusted a group of prostitutes to respect his privacy. The girls recorded their sadomasochistic romp, leaving the ex F1 chief red-faced and litigious. Now, thanks to a French court, his shame is Google's headache. To hide the evidence of his escapade, the company may have to spend a whole lot more than the $4,000 Mosley shelled out to the hookers.

A French court has ruled that Google must automatically block links to nine images of Max Mosley participating in an orgy, according to press reports. Mosley is the former president of the International Automobile Federation.

The company reportedly must find a way to prevent all links to the images from appearing in its image search results for a period of five years. The order takes effect two months after the ruling, presumably to allow Google time to build a filter tool.

The company will be fined 1,000 euros (US$1,344) every time one of the images is found through its search engine, starting next year, the court reportedly ruled.

Google previously argued such a ruling would be tantamount to "automated censorship" of the Web.

Privacy vs. Free Speech

In 2008, the British tabloid News of the World published a video and story relating to a "sick Nazi orgy" in which Mosley participated. He admitted taking part in sadomasochistic activity with five women and paying them, but brushed off accusations of there being a Nazi theme and claimed the video breached his privacy.

Later that year, a UK court ruled the News of the World had breached his privacy and said there was no public interest in printing the story. He was awarded US$94,000 in damages.

In 2011, Mosley won a similar ruling against the now-defunct newspaper's publisher, News Corp., in France.

For companies that operate in multiple countries, having to deal with privacy and free speech laws that vary in different regions "makes day-to-day operations quite complicated and difficult," Anupam Chander, professor and scholar in the law of globalization and digitization at UC Davis School of Law, told TechNewsWorld.

"Anyone who has the means, as Mosley does, will resort to court orders," he added, in order to have perhaps unflattering content about themselves removed from Google results.

The ruling would force it to create a software filter to automatically detect and block the images, Google said. Because it cannot stop others from reposting them on the Web, it would essentially be compelled to act as gatekeeper, tracking where people were posting the images and stopping others from accessing them through Google's services.

Not Our Job

In September, Google said it had removed hundreds of links on Mosley's behalf, following its standard process of scrubbing links to certain pages after the content has been deemed to violate the law.

The French ruling forces Google to take a more proactive approach in purging the Mosley images.

Google is merely a platform for helping people find content, and it should not be responsible for policing links, it has argued.

Banning the images from appearing in its search results would not stop people from accessing them through other means, such as on social networks or other search engines, Google has pointed out.

It reportedly plans to appeal the French court's ruling, which also ordered payment to Mosley of a token 1 euro ($1.34) in damages and 5,000 euros ($6,717) in costs.

"Google is obliged to follow the law in countries where they have boots on the ground, where they have servers or where they have employees," Eva Galperin, a global policy analyst with the Electronic Frontier Foundation, told TechNewsWorld.

"Certainly, Google does have boots on the ground in France, and so they are obliged to follow French law," she continued. However, "the thing they are being asked to do is so technically difficult and potentially expensive that there's no doubt Google will appeal this decision."

Source: http://www.technewsworld.com/rsstory/79382.html
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FDA awards $2.25M grant to study immunosuppresive drug in high-risk patients

PUBLIC RELEASE DATE:

7-Nov-2013

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Contact: Katy Cosse
kathryn.cosse@uc.edu
513-558-0207
University of Cincinnati Academic Health Center

Retrospective and prospective studies will examine conversion to generic tacrolimus in transplant patients

CINCINNATITransplant researchers at the University of Cincinnati (UC) have received a grant from the U.S. Food and Drug Administration to study the safety and efficacy of a generic immunosuppressive drug in high-risk transplant patients.

Rita Alloway, PharmD, UC research professor of medicine and director of transplant clinical research within the UC Department of Internal Medicine, received a $2.25 million FDA grant to run two clinical trials studying the effects of immunosuppressant tacrolimus (Prograf and generics) in high-risk transplant patients.

Tacrolimus is a "cornerstone drug" in post-transplant immunosuppression, used after transplant to reduce the activity of the patient's immune system and lower the risk of rejection. Generic versions were introduced in 2009. Currently Alloway estimates more than 70 percent of transplant patients are dispensed generic tacrolimus.

"The largest concern for clinicians is the switchability between various generics," says Alloway. "When patients receive their prescription, they could be getting medication from different manufacturers each month. Most immunosuppressant drugs require individualized dosing and careful management to ensure the proper blood concentrations are maintainedtoo high exposure to these drugs increases the risk of toxicity, over-immunosuppression and cancer in patents. Too low exposure may lead to rejection of the organ by the patient's immune system."

The three-year grant will support retrospective and prospective studies in high-risk transplant recipients who have converted from branded tacrolimus to a generic version.

In the retrospective study, transplant recipients will be assessed one year prior and one year post conversion to the generic, with researchers assessing their tacrolimus dose changes, incidence of rejection, hospital admission, changes in renal function and changes in transplanted organ function.

The prospective study will compare the bioavailability and steady-state pharmacokinetics of six tacrolimus formulations in a six-way cross-over study. This study will compare patients who express the CYP3A5 enzyme and those who do not, as CYP3A5 expressors have been shown to require larger doses of tacrolimus to attain therapeutic blood concentrations.

Preliminary data from Alloway's tacrolimus research has suggested a link between CYP3A5 expression and peak tacrolimus levels after dosing in generic tacrolimus formulations.

"This study will analyze an enriched patient population based upon genetic factors which predispose the patient to be high risk and most likely to experience problems with generic switching if problems exist," states Alloway.

In 2012, Alloway received a $2.7 million grant from the FDA to study whether the two most disparate generic versions of tacrolimus are bioequivalent to the branded, or innovator, version of the drug in stable transplant patients.

"The results of these studies should address public concerns regarding the use of generic tacrolimus formulations in transplant recipients and provide the transplant clinician and recipients with objective data to address their concerns," she says.

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

PUBLIC RELEASE DATE:

7-Nov-2013

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Contact: Katy Cosse
kathryn.cosse@uc.edu
513-558-0207
University of Cincinnati Academic Health Center

Retrospective and prospective studies will examine conversion to generic tacrolimus in transplant patients

CINCINNATITransplant researchers at the University of Cincinnati (UC) have received a grant from the U.S. Food and Drug Administration to study the safety and efficacy of a generic immunosuppressive drug in high-risk transplant patients.

Rita Alloway, PharmD, UC research professor of medicine and director of transplant clinical research within the UC Department of Internal Medicine, received a $2.25 million FDA grant to run two clinical trials studying the effects of immunosuppressant tacrolimus (Prograf and generics) in high-risk transplant patients.

Tacrolimus is a "cornerstone drug" in post-transplant immunosuppression, used after transplant to reduce the activity of the patient's immune system and lower the risk of rejection. Generic versions were introduced in 2009. Currently Alloway estimates more than 70 percent of transplant patients are dispensed generic tacrolimus.

"The largest concern for clinicians is the switchability between various generics," says Alloway. "When patients receive their prescription, they could be getting medication from different manufacturers each month. Most immunosuppressant drugs require individualized dosing and careful management to ensure the proper blood concentrations are maintainedtoo high exposure to these drugs increases the risk of toxicity, over-immunosuppression and cancer in patents. Too low exposure may lead to rejection of the organ by the patient's immune system."

The three-year grant will support retrospective and prospective studies in high-risk transplant recipients who have converted from branded tacrolimus to a generic version.

In the retrospective study, transplant recipients will be assessed one year prior and one year post conversion to the generic, with researchers assessing their tacrolimus dose changes, incidence of rejection, hospital admission, changes in renal function and changes in transplanted organ function.

The prospective study will compare the bioavailability and steady-state pharmacokinetics of six tacrolimus formulations in a six-way cross-over study. This study will compare patients who express the CYP3A5 enzyme and those who do not, as CYP3A5 expressors have been shown to require larger doses of tacrolimus to attain therapeutic blood concentrations.

Preliminary data from Alloway's tacrolimus research has suggested a link between CYP3A5 expression and peak tacrolimus levels after dosing in generic tacrolimus formulations.

"This study will analyze an enriched patient population based upon genetic factors which predispose the patient to be high risk and most likely to experience problems with generic switching if problems exist," states Alloway.

In 2012, Alloway received a $2.7 million grant from the FDA to study whether the two most disparate generic versions of tacrolimus are bioequivalent to the branded, or innovator, version of the drug in stable transplant patients.

"The results of these studies should address public concerns regarding the use of generic tacrolimus formulations in transplant recipients and provide the transplant clinician and recipients with objective data to address their concerns," she says.

###

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2013-11/uoca-fa110713.php
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New video emerges of ranting Toronto mayor

Toronto Mayor Rob Ford makes a statement to the media outside his office at Toronto's city hall after the release of a video on Thursday Nov. 7, 2013. A new video surfaced showing Ford in a rage, using threatening words including "kill" and "murder." Ford said he was “extremely, extremely inebriated" in the video, which appeared Thursday on the Toronto Star’s website. The context of the video is unknown and it's unclear who the target of Ford's wrath is. (AP Photo/The Canadian Press, Chris Young)

Toronto Mayor Rob Ford makes a statement to the media outside his office at Toronto's city hall after the release of a video on Thursday Nov. 7, 2013. A new video surfaced showing Ford in a rage, using threatening words including "kill" and "murder." Ford said he was “extremely, extremely inebriated" in the video, which appeared Thursday on the Toronto Star’s website. The context of the video is unknown and it's unclear who the target of Ford's wrath is. (AP Photo/The Canadian Press, Chris Young)

Toronto Mayor Rob Ford makes a statement to the media outside his office at Toronto's city hall after the release of a video on Thursday Nov. 7, 2013. A new video surfaced showing Ford in a rage, using threatening words including "kill" and "murder." Ford said he was “extremely, extremely inebriated" in the video, which appeared Thursday on the Toronto Star’s website. The context of the video is unknown and it's unclear who the target of Ford's wrath is. (AP Photo/The Canadian Press, Chris Young)

Toronto Mayor Rob Ford makes a statement to the media outside his office at Toronto's city hall after the release of a video on Thursday Nov. 7, 2013. A new video surfaced showing Ford in a rage, using threatening words including "kill" and "murder." Ford said he was “extremely, extremely inebriated" in the video, which appeared Thursday on the Toronto Star’s website. The context of the video is unknown and it's unclear who the target of Ford's wrath is. (AP Photo/The Canadian Press, Chris Young)

Toronto Mayor Rob Ford talks to a staff member at city hall Wednesday, Nov. 6, 2013 in Toronty. City councilors called on the deputy mayor to "orchestrate a dignified" departure for Ford, who was greeted by angry protesters on his first day of work after acknowledging he smoked crack. Ford took a back stairway to his office to avoid a crush of media and protestors. (AP Photo/The Canadian Press, Chris Young)

Toronto Mayor Rob Ford leaves Toronto's city hall Wednesday, Nov. 6, 2013 in Toronto. City councilors called on the deputy mayor to "orchestrate a dignified" departure for Ford, who was greeted by angry protesters on his first day of work after acknowledging he smoked crack. Ford took a back stairway to his office to avoid a crush of media and protestors. (AP Photo/The Canadian Press, Chris Young)

TORONTO (AP) — A new video that surfaced Thursday shows Toronto Mayor Rob Ford in a rambling rage, using threatening words including "kill" and "murder," as the saga that has gripped Canadians for months took yet another twist.

The mayor told reporters moments after the video was posted online that he was "extremely, extremely inebriated" in it and "embarrassed" by it. The context of the video is unknown and it's unclear who the target of Ford's wrath is. The video, which appeared at length on the Toronto Star's website and in clips on the Toronto Sun's website, prompted another round of calls for Ford to step down.

It's been a whirlwind of a week for Ford, who on Tuesday admitted to smoking crack in a "drunken stupor" about a year ago. Police said last week they had obtained a different, long-sought video that shows Ford smoking a crack pipe.

Police obtained that video in the course of a massive drug investigation into the mayor's friend and occasional driver.

Despite immense pressure from allies and critics, the mayor of North America's fourth largest city has refused to resign or take a leave of absence.

Ford said Thursday he made mistakes and "all I can do is reassure the people. I don't know what to say."

"When you are in that state ... I hope none of you have ever or will ever be in that state," Ford said.

"It's extremely embarrassing. The whole world is going to see it."

In the new video, a visibly agitated Ford paces around, waves his arms and rolls up his sleeves as he says he'll "make sure" the unknown person is dead.

Ford tells another person in the room, possibly the man filming the video, that he wants to "kill" someone in an expletive-laced rant. "Cause I'm going to kill that (expletive) guy," Ford says. "No holds barred brother. He dies or I die."

At one point he says "My brothers are, don't tell me we're liars, thieves, birds?" and then later refers to "80-year-old birds."

The Toronto Star that it purchased the video from "a source who filmed it from someone else's computer" and that "the person with the computer was there in the room."

City Councilor James Pasternak urged Ford to make a "dignified exit."

"The video is very disturbing," he said. "It's very upsetting, it's very sad."

City Councilor Giorgio Mammoliti, a Ford ally, urged the mayor to enter rehab and said in a statement he fears "that if the mayor does not get help now he will succumb to health issues related to addiction."

Ford lawyer Dennis Morris told The Associated Press the context of the video "is skeletal."

"What we have to do is find out when it was taken," he said. "Was it taken eight, 10 months ago or a short time ago? I'm going to try to find that out too. Maybe the Toronto Star knows better."

Asked if Ford told him about the tape, Morris said: "I can't comment, but I don't think we really know."

Earlier Thursday, Morris said he was in talks with the police for Ford to view the video that shows the mayor smoking crack, as city councilors stepped up their efforts to force him from office.

The mayor's travails were taking their toll on his supporters. Canada's finance minister became emotional when asked about Ford, a longtime friend.

Police are seeking to question Ford. Morris previously said Ford would be willing to go view the tape but would not answer questions.

Police have not charged Ford, saying the video didn't provide enough evidence against him. A police spokesman declined to comment.

Municipal law makes no provision for the mayor's forced removal from office unless he's convicted and jailed for a criminal offence.

City Councilor Denzil Minnan-Wong, a member of Ford's executive committee, said Thursday he plans to amend a motion he has filed that would ask Ford to take a leave of absence. The amendment takes the unprecedented step of asking the province of Ontario to pass legislation to remove the mayor if he does not agree to take a leave of absence. The measure could be voted on next Wednesday.

The province, however, has no plans to step in and amend the law to allow Ford to be forced from office, Ontario Municipal Affairs Minister Linda Jeffrey reaffirmed Thursday.

Premier Kathleen Wynne has said she's concerned that Ford's personal issues were making it difficult for the city to carry on normally. But she said it was up to police, the courts or the mayor to take action.

Ford acknowledged a drinking problem for the first time Sunday, saying on his radio show that he was "hammered" in public at a street festival in August and "out of control" drunk, carrying a half empty bottle of brandy around city hall after St. Patrick's Day last year. He then made his stunning confession to reporters Tuesday that he had smoked crack while drunk.

The mayor has called on police to release the tape, but police said they are prohibited from doing so because it is evidence before the courts. Police said the video will come out when Ford associate Alexander Lisi goes to trial on drug and extortion charges.

Toronto Police Chief Bill Blair has also said police have a second tape, but he has declined to discuss what's on it. Police spokesman Mark Pugash told the AP the video released Thursday is not the tape Blair talked about.

The allegations about Ford smoking crack first emerged earlier this year when reporters from the Toronto Star and the U.S. website Gawker separately said they saw that video, but they did not obtain a copy.

___

Follow Rob Gillies on Twitter at —http://twitter.com/rgilliescanada

Associated PressSource: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-11-07-Canada-Toronto%20Mayor/id-fc26f8666e154cd2b060901a752a0438
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AP sources: Kerry to join Iran nuclear talks

GENEVA (AP) — Officials say U.S. Secretary of State John Kerry will fly to Geneva on Friday to participate in nuclear negotiations with Iran and other major powers.

The officials say Kerry will travel to the talks after a brief stop in Israel, where he will hold a third meeting with Israeli Prime Minister Benjamin Netanyahu. Israel's intense interest in Iran's nuclear ambitions is a likely topic between Netanyahu and Kerry as well as Israeli-Palestinian peace.

Iran's plan to cap some of the country's atomic activities in exchange for selective relief from crippling economic sanctions has been accepted by six world powers, the country's chief nuclear negotiator said Thursday.

Kerry's last-minute decision to join the talks suggests a deal could be imminent.

The officials spoke on condition of anonymity because Kerry has not been formally invited by the Europeans to join the talks.

Associated PressSource: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-11-07-EU-Kerry-Iran/id-67e555ae9c624fc2a06d3ae4040adbae
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What I'm using: The Zens Wireless Charger with the Nexus 5

 

Oh, wireless charging, how I missed you. Having used the HTC One and Moto X for the past 8 months or so, I'd been resigned to plugging in my phone every night. Not a huge deal, of course, but it does become a bit of a pain if you're like me and tend to top off at your desk while you're working.

The Nexus 5 can charge wirelessly, of course. That is, you don't actually have to plug the phone to do so. There are any number of wireless charges out there — and if you have one that's Qi-compatiable, you should be good to go. But I've very much been enjoying the Zens Wireless Charger of late, as provided by our pals at ShopAndroid.com.

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Source: http://feedproxy.google.com/~r/androidcentral/~3/e0sZRuqpKmA/story01.htm
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